Sasori is a powerful and skilled anime villain — a renowned puppet master ninja who, like many members of Akatsuki, gained their powers through tragedy. Sasori's parents were killed when he was a child, and he was sent to live with his grandmother - who introduced him to puppetry as an emotional outlet. Many years later, Sasori fought in the Third Great Ninja War where he discovered that the puppets were a great tool for killing enemies, earning him the moniker "Sasori of the Red Sand."
Over time, Sasori transformed himself into a puppet; he was a shell of a human. Because of this, Sasori is immune to aging, lethal attacks, poisons, and even Genjustu. Sasori's "Red Secret Technique: Performance of a Hundred Puppets" allowed him to control a hundred puppets at once, a move so powerful he once single-handedly conquered an entire nation with it. His childhood and what came next turned Sasori into an antagonist of sorts, most notably when he assassinated the Third Kazekage and turned him, too, into a puppet. The only way to fight off this defense is by completely destroying the puppet he is in.